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Table 5 Compiled data of coefficients of independent variables and their associated probability (p) value

From: Development of nitazoxanide-loaded colon-targeted formulation for intestinal parasitic infections: centre composite design-based optimization and characterization

Response

Intercept

A

B

AB

A2

B2

Particle size

892.979

57.905

− 28.9317

− 17.4725

− 143.828

− 5.95833

p values

 

0.0002

0.0012

0.0093

< 0.0001

0.2445

Percentage yield

83.4233

6.87667

1.97833

− 0.035

− 1.75

− 0.425

p values

 

< 0.0001

0.0014

0.8781

0.0097

0.2474

Entrapment efficiency

88.0856

2.42667

3.40833

1.095

− 4.52333

0.0316667

p values

 

0.0070

0.0026

0.0922

0.0057

0.9633