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Table 3 Structural proteins of coronavirus and their functions

From: COVID-19 pandemic crisis—a complete outline of SARS-CoV-2

Structural proteins Functions of proteins
Spike protein (S) Virus and host cell fusion by binding
Membrane protein (M) Nutrient transport, determines shape, and formation of envelope
Envelope protein (E) Interferes with host immune response
Nucleocapsid protein (N) Binds with RNA genome and makes up nucleocapsid
Hemagglutinin-esterase (HE) Binds sialic acids on surface glycoprotein
  1. According to the recent studies, it is observed that coronavirus which lacks envelope protein (E) serves as a good candidate in vaccine designing