Table 5 In vitro floating properties and tabletting characteristics of Nizatidine EGFMT
From: Design, statistical optimization of Nizatidine floating tablets using natural polymer
EGMFT | FLT (s) | TFT (h) of weighta | Uniformity of weighta | Uniformity contentb (%) | Hardnessc (kg/cm2) | Friability (%) |
|---|---|---|---|---|---|---|
FNM1 | 9 | 14 | 190.0 ± 1.97 | 102.92 ± 1.05 | 4–5 | 0.06 |
FNM2 | 5 | 13 | 198.5 ± 2.91 | 99.44 ± 1.34 | 4–5 | 0.13 |
FNM3 | 2 | 12 | 207 ± 1.42 | 101.4 ± 1.45 | 4–5 | 0.17 |
FNM4 | 14 | 18 | 284.5 ± 1.34 | 98.24 ± 1.76 | 4–5 | 0.09 |
FNM5 | 8 | 18 | 297.25 ± 0.4 | 96.52 ± 0.09 | 4–5 | 0.14 |
FNM6 | 6 | 16 | 310.0 ± 0.98 | 99.64 ± 0.47 | 4–5 | 0.03 |
FNM7 | 18 | 24 | 379.0 ± 1.56 | 98.64 ± 0.97 | 4–5 | 0.15 |
FNM8 | 13 | 24 | 396.0 ± 1.45 | 99.82 ± 1.57 | 4–5 | 0.19 |
FNM9 | 8 | 24 | 413.0 ± 1.31 | 97.12 ± 1.85 | 4–5 | 0.17 |
FNW1 | 5 | 8 | 190.1 ± 1.23 | 99.95 ± 1.48 | 4–5 | 0.08 |
FNW2 | 3 | 8 | 198.5 ± 1.75 | 103.40 ± 0.15 | 4–5 | 0.16 |
FNW3 | 1 | 8 | 207.0 ± 0.93 | 101.52 ± 1.57 | 4–5 | 0.19 |
FNW4 | 7 | 11 | 284.5 ± 0.2 | 99.92 ± 1.49 | 4–5 | 0.17 |
FNW5 | 5 | 10 | 297.25 ± 1.6 | 97.30 ± .049 | 4–5 | 0.18 |
FNW6 | 4 | 10 | 310.0 ± 1.24 | 99.66 ± 0.15 | 4–5 | 0.06 |
FNW7 | 13 | 13 | 379.0 ± 0.97 | 99.92 ± 1.43 | 4–5 | 0.01 |
FNW8 | 10 | 12 | 396.0 ± 0.98 | 97.60 ± 1.46 | 4–5 | 0.03 |
FNW9 | 5 | 12 | 413.0 ± 1.46 | 99.74 ± 1.54 | 4–5 | 0.15 |