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Table 1 In vivo anthelmintic effect of C. compressus methanolic root extract* on adult stages of H. diminuta infection in rats

From: Evaluation of in vitro and in vivo anthelmintic efficacy of Cyperus compressus Linn., a traditionally used anthelmintic plant in parasite-animal models

Treatment groups (mg/kg) EPG (mean ± SEM) Percentage difference in EPG (A–B) Worm count at necropsy (mean ± SEM) Percentage reduction in worm count (%)
Pre-treatment 18–20 days (A) Post-treatment 26–28 days (B)
Control 21676 ± 195.22 21923 ± 26.07 1.13 5.0 ± 0.00 0
Plant extract
 175 21652 ± 105.29 14303 ± 110.51ab − 33.94 4.4 ± 0.24 12
 350 22663 ± 119.43 12561 ± 122.27ab − 44.57 4.2 ± 0.37 16
 700 22583 ± 102.33 8368 ± 192.61ab − 61.74 3.8 ± 0.20 24
Praziquantel
 5 22000 ± 221.14 3057 ± 48.26ab − 86.10 0.6 ± 0.24a 88
  1. *Administration of plant extract and praziquantel on days 21−25 post-inoculation with five cysticercoids/rat (n = 5)
  2. ap < 0.001 as compared to control value
  3. bp < 0.001 as compared to pre-treatment, one-way ANOVA, followed by Tukey’s test