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Table 2 In vivo anthelmintic effect of C. compressus methanolic root extract* on S. obvelata in mice

From: Evaluation of in vitro and in vivo anthelmintic efficacy of Cyperus compressus Linn., a traditionally used anthelmintic plant in parasite-animal models

Treatment groups (mg/kg) EPG (mean ± SEM) Percentage difference in EPG Worm count at necropsy Percentage reduction in worm count (%)
Pre-treatment (days 1–3) Post-treatment (days 9–11) Min–Max Mean ± SEM
Control 28.4 ± 0.87 29.8 ± 0.37 4.9 62–114 90.2 ± 9.07 0
Plant extract
 175 26 ± 1.58 22 ± 4.19 − 15.38 42–98 68.2 ± 10.35 24.39
 350 25 ± 1.94 20.4 ± 3.14 − 18.4 41–92 65.4 ± 10.94 27.49
 700 24.2 ± 1.59 17.2 ± 2.98 − 26.61 40–86 59 ± 7.93 33.85
Albendazole
 20 26.4 ± 0.50 4.8 ± 0.37ab − 75.75 4–10 8 ± 0.70a 91.13
  1. *Administration of plant extract and albendazole on days 4–8 after pre-treatment EPG (n = 5)
  2. ap < 0.001 as compared to control value
  3. bp < 0.001 as compared to pre-treatment, one-way ANOVA, followed by Tukey’s test