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Table 1 Effect of EEAS on BUN, creatinine, and uric acid on PCM-induced nephrotoxicity in rats

From: Nephroprotective activity of Annona Squamosa leaves against paracetamol-induced nephrotoxicity in rats: in vitro and in vivo experiments

Group BUN (mg/dl) Creatinine (mg/dl) Uric acid (mg/dl)
Normal 30.89 ± 0.25 5.12 ± 0.008 1.22 ± 0.06
PCM alone 72.17 ± 0.192* 9.13 ± 0.077* 2.05 ± 0.13*
PCM + EEAS(200 mg/kg) 54.2 ± 0.044@@ 3.13 ± 0.112@@ 1.70 ± 0.06@@
PCM + EEAS (400 mg/kg) 38.5 ± 0.03@@ 4.57 ± 0.82@@ 1.23 ± 0.03@@
  1. All values were expressed as mean ± SEM, with six animals per group
  2. *PCM-induced one compared with the normal one (P < 0.01)
  3. @@Two different experimental groups compared with the PCM-induced group (P < 0.001)