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Table 2 Effect of EEAS on GSH, SOD, and catalase on PCM-induced nephrotoxicity in rats

From: Nephroprotective activity of Annona Squamosa leaves against paracetamol-induced nephrotoxicity in rats: in vitro and in vivo experiments

Group

GSH (nmol/g protein)

SOD (U/g protein)

Catalase (U/g protein)

Normal

68.16 ± 0.24

51.24 ± 3.11

55.01 ± 0.53

PCM alone

36.80 ± 0.14*

29.17 ± 1.58*

21.21 ± 0.09*

PCM + EEAS (200 mg/kg)

43.36 ± 0.73@@

40.33 ± 2.61@@

38.58 ± 0.19@@

PCM + EEAS (400 mg/kg)

60.95 ± 0.08@@

47.79 ± 2.14@@

49.54 ± 0.14@@

  1. All values were expressed as mean ± SEM with six animals in a group
  2. *PCM-induced group compared with the normal group (P < 0.01)
  3. @@Two different experimental groups compared with the PCM-induced group (P < 0.001)