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Table 2 Effect of EEAS on GSH, SOD, and catalase on PCM-induced nephrotoxicity in rats

From: Nephroprotective activity of Annona Squamosa leaves against paracetamol-induced nephrotoxicity in rats: in vitro and in vivo experiments

Group GSH (nmol/g protein) SOD (U/g protein) Catalase (U/g protein)
Normal 68.16 ± 0.24 51.24 ± 3.11 55.01 ± 0.53
PCM alone 36.80 ± 0.14* 29.17 ± 1.58* 21.21 ± 0.09*
PCM + EEAS (200 mg/kg) 43.36 ± 0.73@@ 40.33 ± 2.61@@ 38.58 ± 0.19@@
PCM + EEAS (400 mg/kg) 60.95 ± 0.08@@ 47.79 ± 2.14@@ 49.54 ± 0.14@@
  1. All values were expressed as mean ± SEM with six animals in a group
  2. *PCM-induced group compared with the normal group (P < 0.01)
  3. @@Two different experimental groups compared with the PCM-induced group (P < 0.001)