Table 5 Genes whose variants increase the risk of DM and CVD
From: Diabetes and cardiovascular disease: inter-relation of risk factors and treatment
Gene | Protein function |
|---|---|
TCF7L2 | |
PHACTR1 | Phosphatase and actin regulator 1. It involves the reorganization of the actin [108] |
HMGA1 | High-mobility group A1. Involved in glucose metabolism and cell growth differentiation [109, 110] |
Paraoxonase | |
Adiponectin | Adipokine with anti-atherogenic and anti-inflammatory effects [113] |
CDKN2A/2B | Cyclin-dependent kinase inhibitor. Cell cycle regulation [108] |