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Future Journal of Pharmaceutical Sciences

Table 1 Composition and physicochemical characterization of quetiapine loaded nanoparticles (QNP) (data represents mean ± SD, n = 3)

From: Comparative evaluation of intranasally delivered quetiapine loaded mucoadhesive microemulsion and polymeric nanoparticles for brain targeting: pharmacokinetic and gamma scintigraphy studies

Formulations

CH:TPP mass ratioa

Drug (% w/v)

Drug loading (%)

Size (nm)

PDI

Zeta potential (mV)

pH

Viscosity (cP)

QNP

4.8:1

1

64.29 ± 2.12

131.08 ± 7.45

0.252 ± 0.064

34.4 ± 1.87

5.87 ± 0.11

7.54 ± 0.22

  1. aConcentration of CH and TPP remains 0.1% w/v
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