From: Development and validation of a simple and rapid ICP-OES method for quantification of elemental impurities in voriconazole drug substance
Elemental impurity
Mean value of element (μg/g)
% Difference
Controlled sample
Spiked sample
Lead
0.55
0.0
Palladium
0.91
0.84
8.0
Zinc
128.0
125.9
1.7