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Table 3 Polymer blends used in film coatings

From: Applications of polymer blends in drug delivery

Polymers Advantage(s) Commercial product/application Ref.
Polyvinyl alcohol, polyethylene glycol (PEG) 3350 PEG 3350 can be used as a dry powder plasticizer for fully formulated coating systems Opadry II 85F [5]
Hypromellose, hydroxypropyl cellulose Improved adhesion, increased film elasticity SheffCoat™ HS [6]
Hypromellose, polyvinyl alcohol Improved mositure protection, increased film elasticity SheffCoat™ MP [6]
Hypromellose, polydextrose or starch Cost reduction; shorter ccoating times due to higher spray solids contents due lower viscosity SheffCoat™ D (HPMC/polydextrose)
SheffCoat™ S (HPMC/starch)
[6]
P-MAA-EA, P-EA-MMA Increased film flexibility, eliminates plasticizer requirments and facilates the compression of enteric coated particles Eudragit® FL 30 D-55 [7]
P-EA-MMA-TMAEMA (1:2:0.2), P-EA-MMA-TMAEMA (1:2:0.1) Modulation of drug release rates Eudragit® RL and RS combinations for sustained release [8]
Ethylcellulose, sodium alginate Alginate serves as a pH-dependent pore former and provides enteric functionality, GRAS excipient-based enteric film coating for nutraceuticals Nutrateric® [9]
  1. Abbreviations: P-MAA-EA poly(methacrylic acid-co-ethyl acrylate) (1:1), P-EA-MMA poly(ethyl acrylate-co-methyl methacrylate) (2:1), P-EA-MMA poly(ethyl acrylate-co-methyl methacrylate), P-EA-MMA-TMAEMA poly(ethyl acrylate-co-methyl methacrylate-co-trimethylammonioethyl methacrylate chloride), GRAS generally regarded as safe