Skip to main content

Table 3 Polymer blends used in film coatings

From: Applications of polymer blends in drug delivery

Polymers

Advantage(s)

Commercial product/application

Ref.

Polyvinyl alcohol, polyethylene glycol (PEG) 3350

PEG 3350 can be used as a dry powder plasticizer for fully formulated coating systems

Opadry II 85F

[5]

Hypromellose, hydroxypropyl cellulose

Improved adhesion, increased film elasticity

SheffCoatâ„¢ HS

[6]

Hypromellose, polyvinyl alcohol

Improved mositure protection, increased film elasticity

SheffCoatâ„¢ MP

[6]

Hypromellose, polydextrose or starch

Cost reduction; shorter ccoating times due to higher spray solids contents due lower viscosity

SheffCoatâ„¢ D (HPMC/polydextrose)

SheffCoatâ„¢ S (HPMC/starch)

[6]

P-MAA-EA, P-EA-MMA

Increased film flexibility, eliminates plasticizer requirments and facilates the compression of enteric coated particles

Eudragit® FL 30 D-55

[7]

P-EA-MMA-TMAEMA (1:2:0.2), P-EA-MMA-TMAEMA (1:2:0.1)

Modulation of drug release rates

Eudragit® RL and RS combinations for sustained release

[8]

Ethylcellulose, sodium alginate

Alginate serves as a pH-dependent pore former and provides enteric functionality, GRAS excipient-based enteric film coating for nutraceuticals

Nutrateric®

[9]

  1. Abbreviations: P-MAA-EA poly(methacrylic acid-co-ethyl acrylate) (1:1), P-EA-MMA poly(ethyl acrylate-co-methyl methacrylate) (2:1), P-EA-MMA poly(ethyl acrylate-co-methyl methacrylate), P-EA-MMA-TMAEMA poly(ethyl acrylate-co-methyl methacrylate-co-trimethylammonioethyl methacrylate chloride), GRAS generally regarded as safe