Table 1 Composition of nimodipine solid dispersion systems
Formulations | Nimodipine (g) | Compritol ATO 888 (g) | Gelucire 43/01 (g) | Gelucire 39/01 (g) | Precirol ATO 5 (g) | Sylysia 350 (g) |
|---|---|---|---|---|---|---|
F1 | 1 | 0.5 | – | – | – | 0.5 |
F2 | 1 | 1 | – | – | – | 1 |
F3 | 1 | 1.5 | – | – | – | 1.5 |
F4 | 1 | 2 | – | – | – | 2 |
F5 | 1 | 2.5 | – | – | – | 2.5 |
F6 | 1 | – | 0.5 | – | – | 0.5 |
F7 | 1 | – | 1 | – | – | 1 |
F8 | 1 | – | 1.5 | – | – | 1.5 |
F9 | 1 | – | 2 | – | – | 2 |
F10 | 1 | – | 2.5 | – | – | 2.5 |
F11 | 1 | – | – | 0.5 | – | 0.5 |
F12 | 1 | – | – | 1 | – | 1 |
F13 | 1 | – | – | 1.5 | – | 1.5 |
F14 | 1 | – | – | 2 | – | 2 |
F15 | 1 | – | – | 2.5 | – | 2.5 |
F16 | 1 | – | – | – | 0.5 | 0.5 |
F17 | 1 | – | – | – | 1 | 1 |
F18 | 1 | – | – | – | 1.5 | 1.5 |
F19 | 1 | – | – | – | 2 | 2 |
F20 | 1 | – | – | – | 2.5 | 2.5 |