Formulation and development of floating multiple-unit minitablets of Nimodipine without using a gas-generating agent: in vitro and in vivo characterization

Future Journal of Pharmaceutical Sciences

Table 3 Micromertics properties of solid dispersions

Formulations	*Angle of repose (⁰)	*Carr’s index (C.I)	*Hausner’s ratio (H.R)
Nimodipine	42 ± 2.4	29 ± 2.1	1.46 ± 0.8
F1	24.23 ± 2.1	15.62 ± 1.6	1.19 ± 0.4
F2	22.67 ± 1.9	16.18 ± 1.2	1.22 ± 0.7
F3	22.48 ± 2.2	14.42 ± 1.2	1.18 ± 0.2
F4	20.67 ± 1.9	16.89 ± 1.2	1.22 ± 0.7
F5	24.23 ± 2.1	17.62 ± 1.6	1.19 ± 0.4
F6	23.23 ± 2.1	15.62 ± 1.6	1.19 ± 0.4
F7	22.67 ± 1.9	16.89 ± 1.2	1.22 ± 0.7
F8	22.48 ± 2.2	15.39 ± 1.2	1.18 ± 0.2
F9	24.48 ± 2.2	14.32 ± 1.2	1.18 ± 0.2
F10	21.67 ± 1.9	18.89 ± 1.2	1.22 ± 0.7
F11	22.23 ± 2.1	16.62 ± 1.6	1.19 ± 0.4
F12	24.67 ± 1.9	17.89 ± 1.2	1.22 ± 0.7
F13	22.48 ± 2.2	15.46 ± 1.2	1.19 ± 0.2
F14	24.48 ± 2.2	14.25 ± 1.2	1.18 ± 0.2
F15	22.67 ± 1.9	16.89 ± 1.2	1.22 ± 0.7
F16	21.54 ± 2.1	17.13 ± 1.6	1.15 ± 0.4
F17	23.61 ± 1.9	16.16 ± 1.4	1.23 ± 0.3
F18	21.24 ± 3.1	14.31 ± 1.2	1.22 ± 0.2
F19	25.15 ± 2.2	15.16 ± 2.6	1.21 ± 0.2
F20	21.56 ± 1.9	13.14 ± 1.2	1.19 ± 0.7