Pharmacodynamic findings for the usefulness of Luffa cylindrica (L.) leaves in atherosclerosis therapy with supporting antioxidant potential

Future Journal of Pharmaceutical Sciences

Table 2 Effect of methanolic extract of Luffa cylindrica (L.) leaves on Biochemical Parameters in wistar rats

Group	TC (mg/dl)	TG (mg/dl)	HDL (mg/dl)	VLDL (mg/dl)	LDL(mg/dl)
Normal	79.63 ± 2.715	66.05 ± 1.069	38.04 ± 1.960	13.21 ± 0.213	28.38 ± 2.319
Hyperlipidemic (Triton X-100)	149.16 ± 4.467	123.07 ± 5.421	16.45 ± 1.416	24.61 ± 1.084	108.1 ± 16.779
Atorvastatin (10mg/kg)	85.56 ± 6.128**	59.12±7.242***	40.76±1.404***	11.82±1.449**	34.65±4.642***
MELCL (100mg/kg)	92.46 ± 6.032**	77.88 ± 8.178**	38.58±1.767***	15.57±1.759**	37.28±7.254**
MELCL (200mg/kg)	85.48±3.230***	74.62 ± 8.764**	40.58±1.625***	14.92±1.635**	31.97±3.475***

Values are expressed as mean ± S.E.M; n=6, *P<0.05, **P<0.01, ***P<0.001 when group hyperlipidemic control compared with normal and group atorvastatin, MELCL(100mg/kg) and MELCL (200mg/kg) were compared with hyperlipidemic control considered for significance, (ANOVA followed by Dunnett’s test)
MELCL Methanolic extract of Luffa cylindrica (L.) leaves, TC Total Cholesterol, TG Triglycerides, LDL Low-Density Lipoproteins, VLDL Very Low-Density Lipoproteins, HDL High-Density Lipoproteins