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Table 20 Robustness study results of ethanol

From: Determination of residual solvents in paclitaxel by headspace gas chromatography

Parameter System conditions Percentage RSD for peak area (n = 6) Retention time Plate count Tailing factor
Flow rate (± 0.2 mL/min) 2.3 1.7 7.32 79241 1.2
2.5 1.6 6.65 78485 1.1
2.7 1.8 5.98 77142 1.2
Column oven temperature (± 5 °C) 35 °C 1.4 7.29 79520 1.4
40 °C 1.6 6.65 78485 1.1
45 °C 1.5 6.10 80157 1.0
Vial oven temperature (± 5 °C) 85 °C 1.5 6.64 76547 1.3
90 °C 1.6 6.65 78485 1.1
95 °C 1.7 6.63 74215 1.2