Table 7 Linearity and range of solvents
From: Determination of residual solvents in paclitaxel by headspace gas chromatography
S. no. | Percentage level | Ethylacetate | Tetrahydrofuran | DIPEA | |||
|---|---|---|---|---|---|---|---|
Concentration (ppm) | Mean peak area | Concentration (ppm) | Mean peak area | Concentration (ppm) | Mean peak area | ||
1 | LOQ | 501.24 | 178.8986 | 71.0536 | 38.6221 | 2.0984 | 3.018 |
2 | 50 | 2526.45 | 897.493 | 367.268 | 199.1105 | 10.4985 | 15.0979 |
3 | 75 | 3788.5 | 1350.24 | 546.902 | 298.1658 | 15.6401 | 22.648 |
4 | 100 | 5047.5 | 1799.986 | 731.536 | 397.221 | 20.98685 | 30.181 |
5 | 125 | 6311.5 | 2244.733 | 914.17 | 496.2763 | 26.2482 | 37.723 |
6 | 150 | 7574.58 | 2697.479 | 1096.804 | 595.3315 | 31.4706 | 45.269 |