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Table 3 Concentrations of urea and creatinine in rats administered ethanolic extracts of fruits of Xylopia aethiopica and seeds and leaves of Piper guineense

From: Biochemical and histological effects of ethanolic extracts of fruits of Xylopia aethiopica and seeds and leaves of Piper guineense on liver and kidney function in male albino rats

Parameters

Group 1 (normal control)

Group 2 (seeds’ extract of Piper guineense 100 mg/kg bw)

Group 3 (leaves’ extract of Piper guineense 100 mg/kg bw)

Group 4 (fruits’ extract of Xylopia aethiopica 100 mg/kg bw)

Urea (mmol/L)

4.77 ± 0.26a

4.16 ± 0.68a

3.43 ± 0.40b

4.54 ± 0.65a

Creatinine (μmol/L)

18.33 ± 0.25a

27.10 ± 3.58b

16.87 ± 0.75a

19.17 ± 1.68a

  1. Results represent mean ± standard deviation of group serum results obtained (n = 5). Means in the same row, having different letters of the alphabet, are statistically significant (p < 0.05). The concentration of urea showed significant decrease (p < 0.05) in group 3 and non-significant decrease in groups 2 and 4. Creatinine increased significantly (p < 0.05) in group 2 and non-significantly in groups 3 and 4