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Table 4 Aerodynamic assessment of RES-NC-DPI and RES-DPI at a flow rate of 60 L/min (mean ± SD, n = 3)

From: Fabrication and application of dimyristoyl phosphatidylcholine biomaterial-based nanocochleates dry powder inhaler for controlled release resveratrol delivery

Aerodynamic parameters RES-DPI RES-NC-DPI
RD (μg) 1470.67 ± 110.22 1797.50 ± 109.65**
ED (μg) 1281.08 ± 132.44 1557.08 ± 120.22
FPD (μg) 780.08 ± 90.22 986.31 ± 82.43**
FPF (%) 53.04 ± 9.08 54.87 ± 9.32
MB (%) 89.74 ± 7.00 91.60 ± 8.33
MMAD (μm) 2.15 ± 0.99 2.30 ± 1.09
GSD (μm) 3.60 ± 1.22 3.16 ± 1.21
D (%) 60.89 ± 8.89 63.34 ± 9.77
EI 11.84 ± 1.09 11.90 ± 1.03
  1. RD recovered dose, ED emitted dose, FPD fine particle dose, FPF fine particle fraction, MB mass balance, D dispersibility, MMAD mass median aerodynamic diameter, GSD geometric standard deviation, and EI effective inhalation index
  2. **p ≤ 0.01 (statistically significant) when compared to the control group RES-DPI