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Future Journal of Pharmaceutical Sciences
Fig. 5 | Future Journal of Pharmaceutical Sciences

Fig. 5

From: Metformin and asarone inhibit HepG2 cell proliferation in a high glucose environment by regulating AMPK and Akt signaling pathway

Fig. 5

The treatment of high glucose-promoted HepG2 cells with metformin and asarone downregulates the expression of SREBP-1. a A representative flow cytometry histogram events depicting the expression of SREBP-1 cultured in normal glucose (NG; 5.5 mM), high glucose (HG; 25 mM), HG + Metformin HCl, and HG + Asarone. b Bar diagrams represent geometric mean fluorescence intensity (GMFI) of SREBP-1 in HepG2 cells. Values represent mean ± SEM of an experiment done in triplicate; one-way ANOVA followed by Bonferroni test, where ##p < 0.01 and ###p < 0.001 compared to the high glucose (HG) group

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