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Table 1 The IC50 values of metformin HCl and α- and β-asarone based on the MTT assay and dose selected for further studies

From: Metformin and asarone inhibit HepG2 cell proliferation in a high glucose environment by regulating AMPK and Akt signaling pathway

Test compounds

IC50 values in mM (MTT assay)

One half of the IC50 in mM used for detailed studies

Metformin HCl

25.74

12.87

α-Asarone

1.22

0.61

β-Asarone

1.46

0.73