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Future Journal of Pharmaceutical Sciences

Table 7 Robustness study

From: HPLC method validation for quantification of tetrahydrocurcumin in bulk drug and formulation

Parameter

RT

Asymmetry factor

Theoretical plates

% Assay

Change in wavelength

+3 nm

6.61

1.15

5671

98.56

 

−3 nm

6.62

1.17

5661

100.36

Flow rate

+10% ml/min

6.64

1.18

5680

100.17

 

−10% ml/min

6.66

1.18

5652

99.09

Column temperature

+2 °C

6.56

1.16

5627

100.38

 

−2 °C

6.56

1.16

5641

100.33

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