Insights on recent approaches in drug discovery strategies and untapped drug targets against drug resistance

Future Journal of Pharmaceutical Sciences

Table 3 Comparative drug treatment schedule for data of TB/MDR/XDR-TB—cost, duration and success rate

Drug/treatment parameter	Drug susceptible tuberculosis	Drug-resistant tuberculosis
Drug/treatment parameter	Drug susceptible tuberculosis	MDR-TB	XDR-TB	TDR-TB
Isoniazid	Yes	No	No	No
Rifampin	Yes	No	No	No
Fluoroquinolones	Yes	Yes	No	No
Injectable	Yes	Yes	No	No
First line treatment	No	No	Yes	No
Second-line treatment	Yes	No	No	No
Duration of treatment	6 months	2 years	2 years	> 2 years
Cost of therapy	50 $	5000 $	50,000$	> 100,000 $
Percentage rate of cure	90 %	50 %	10 %	0–1 %