Table 6 ANOVA for the quadratic model {cumulative amount of drug permeated in 24 h (Q24) response}
Source | Sum of squares | df | Mean square | F value | p value | |
|---|---|---|---|---|---|---|
Model | 1.198E+07 | 9 | 1.331E+06 | 29.86 | < 0.0001 | Significant |
A-HPMC K15M:ERL100 | 2.175E+06 | 1 | 2.175E+06 | 48.80 | 0.0002 | |
B-Di-butyl pthalate | 41075.66 | 1 | 41075.66 | 0.9214 | 0.3691 | |
C-d-limonene | 9.490E+06 | 1 | 9.490E+06 | 212.88 | < 0.0001 | |
AB | 13157.35 | 1 | 13157.35 | 0.2952 | 0.6038 | |
AC | 1.602E+05 | 1 | 1.602E+05 | 3.59 | 0.0999 | |
BC | 506.30 | 1 | 506.30 | 0.0114 | 0.9181 | |
A2 | 4649.90 | 1 | 4649.90 | 0.1043 | 0.7562 | |
B2 | 21226.92 | 1 | 21226.92 | 0.4762 | 0.5124 | |
C2 | 65378.56 | 1 | 65378.56 | 1.47 | 0.2652 | |
Residual | 3.120E+05 | 7 | 44577.82 | |||
Lack of Fit | 86074.35 | 3 | 28691.45 | 0.5079 | 0.6978 | Not significant |
Pure error | 2.260E+05 | 4 | 56492.60 | |||
Cor total | 1.229E+07 | 16 |