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Table 8 Skin irritation studies on Wistar male rat

From: Development, optimization and characterization of flurbiprofen matrix transdermal drug delivery system using Box–Behnken statistical design

Group

Visual observation

Erythema

Oedema

Negative control

0.00 ± 0.000

0.00 ± 0.000

Adhesive tape

0.91 ± 0.023

0.58 ± 0.016

FBPT7 transdermal film

0.16 ± 0.065

0.41 ± 0.047

Formalin

3.33 ± 0.084

3.25 ± 0.72

  1. Values are expressed as mean ± S.D., n = 3