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Table 4 Effect of Cola hispida leaf ethyl acetate fraction on MDA, CAT, SOD, and GPx in heart tissues of rats

From: Ethyl acetate fraction of Cola hispida leaf protects against doxorubicin-induced myocardial injury in male albino rats

Groups MDA (nmols g−1 protein) CAT (Umg−1 protein) SOD (Umg−1 protein) GPx (Umg−1 protein)
Normal control 2.35±0.32a 3.71 ± 0.19ab 11.38 ± 0.03b 227.48 ± 21.67a
Dox only 3.89±0.37c 3.09 ± 1.13a 10.87 ± 0.54a 174.90 ± 16.98c
100 mg kg−1 bw Vit. E + Dox 2.85±0.51b 4.57 ± 0.34c 11.39 ± 0.04b 195.75 ± 10.41b
100 mg kg−1 bw fraction + Dox 3.78±0.44b 3.70 ± 0.59ab 11.36 ± 0.16b 174.95 ± 3.93a
200 mg kg−1 bw, fraction + Dox 3.10±0.75ab 4.39 ± 0.43bc 11.39 ± 0.05b 181.57 ± 7.01ab
400 mg kg−1 bw, fraction + Dox 2.62±1.10a 4.83 ± 0.19c 11.40 ± 0.18b 196.67 ± 6.12b
  1. Results are expressed as mean ± SD. n=5. Values in the same column having different superscripts differ significantly (p<0.05)
  2. MDA malondialdehyde, CAT catalase, SOD superoxide dismutase, GPx glutathione peroxidase