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Table 4 Effect of Cola hispida leaf ethyl acetate fraction on MDA, CAT, SOD, and GPx in heart tissues of rats

From: Ethyl acetate fraction of Cola hispida leaf protects against doxorubicin-induced myocardial injury in male albino rats

Groups

MDA (nmols g−1 protein)

CAT (Umg−1 protein)

SOD (Umg−1 protein)

GPx (Umg−1 protein)

Normal control

2.35±0.32a

3.71 ± 0.19ab

11.38 ± 0.03b

227.48 ± 21.67a

Dox only

3.89±0.37c

3.09 ± 1.13a

10.87 ± 0.54a

174.90 ± 16.98c

100 mg kg−1 bw Vit. E + Dox

2.85±0.51b

4.57 ± 0.34c

11.39 ± 0.04b

195.75 ± 10.41b

100 mg kg−1 bw fraction + Dox

3.78±0.44b

3.70 ± 0.59ab

11.36 ± 0.16b

174.95 ± 3.93a

200 mg kg−1 bw, fraction + Dox

3.10±0.75ab

4.39 ± 0.43bc

11.39 ± 0.05b

181.57 ± 7.01ab

400 mg kg−1 bw, fraction + Dox

2.62±1.10a

4.83 ± 0.19c

11.40 ± 0.18b

196.67 ± 6.12b

  1. Results are expressed as mean ± SD. n=5. Values in the same column having different superscripts differ significantly (p<0.05)
  2. MDA malondialdehyde, CAT catalase, SOD superoxide dismutase, GPx glutathione peroxidase