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Table 1 Cyclooxygenase inhibitory activity of sydnone 3758 and 6163

From: Discovery of Bis-sydnone styryl ketone as a selective cyclooxygenase-2 inhibitor

  1. SI-2: COX-2 selectivity index. The final concentration of the study compounds in the COX reaction tubes was 200 μM. Standard drugs (SC-560 and DuP-697) were used at their recommended IC50 values