Therapeutic role of corticosteroids in COVID-19: a systematic review of registered clinical trials

Raju, Reshma; V., Prajith; Biatris, Pratheeksha Sojan; J., Sam Johnson Udaya Chander

doi:10.1186/s43094-021-00217-3

Future Journal of Pharmaceutical Sciences

Table 2 Methodological quality of included trials

From: Therapeutic role of corticosteroids in COVID-19: a systematic review of registered clinical trials

Trial identifier	Estimated sample size	Allocation (randomized/non-randomized)	Blinding/masking	Study design
NCT04438980	72	Randomized	Double	Interventional
NCT04435795	454	Randomized	Triple	Interventional
NCT04425863	10	Not available	Not available	Non-interventional, prospective cohort
NCT04416399	478	Randomized	Open label	Interventional
NCT04411667	40	Randomized	Open label	Interventional
NCT04395105	284	Randomized	Open label	Interventional
NCT04394182	15	Not available	Open label	Interventional
NCT04381936	12000	Randomized	Open label	Interventional
NCT04348305	1000	Randomized	Quadruple	Interventional
NCT04331054	436	Randomized	Open label	Interventional
NCT04360876	90	Randomized	Double	Interventional
NCT04355247	20	Not available	Open label	Interventional
NCT04381364	446	Randomized	Open label	Interventional
NCT04380818	106	Non-randomized	Open label	Interventional
NCT04377711	400	Randomized	Double	Interventional
NCT04377503	40	Randomized	Open label	Interventional
NCT04374474	75	Randomized	Open label	Interventional
NCT04366115	126	Randomized	Open label	Interventional
NCT04361474	120	Randomized	Single	Interventional
NCT04359511	210	Randomized	Single	Interventional
NCT04355637	300	Randomized	Open label	Interventional
NCT04349410	500	Randomized	Single	Interventional
NCT04347980	122	Randomized	Single	Interventional
NCT04263402	100	Randomized	Single	Interventional
NCT04193878	600	Randomized	Triple	Interventional
NCT03852537	90	Randomized	Double	Interventional
NCT02735707	7100	Randomized	Open label	Randomized, multifactorial trial
NCT04345445	310	Randomized	Open label	Interventional
NCT04344730	550	Randomized	Quadruple	Interventional
NCT04344288	304	Randomized	Open label	Interventional
NCT04343729	425	Randomized	Quadruple	Interventional
NCT04341038	84	Randomized	Single	Interventional
NCT04331470	30	Randomized	Double	Interventional
KCT0005105	141	Randomized	Open label	Interventional
NCT04329650	200	Randomized	Open label	Interventional
NCT04327401	350	Randomized	Open label	Interventional
NCT04325061	200	Randomized	Open label	Interventional
NCT04323592	173	Non-randomized	Open label	Non-interventional, prospective cohort
NCT04374071	250	Non-randomized	Not available	Non-interventional, retrospective cohort
NCT04244591	80	Randomized	Open label	Interventional
NCT04273321	86	Randomized	Open label	Interventional
IRCT20080901001165N52	50	Randomized	Open label	Interventional
IRCT20200406046963N1	40	Randomized	Open label	Interventional
IRCT20200404046947N1	68	Randomized	Single	Interventional
IRCT20081027001411N3	60	Randomized	Single	Interventional
IRCT20120215009014N354	81	Randomized	Double	Interventional
IRCT20200204046369N1	48	Non-randomized	Open label	Interventional
IRCT20200318046812N2	906	Randomized	Open label	Interventional
IRCT20151227025726N17	48	Randomized	Open label	Interventional
IRCT20120225009124N4	105	Randomized	Open label	Interventional
ChiCTR2000029386	24	Randomized	Not available	Interventional
ChiCTR2000029656	50	Randomized	Open label	Interventional
ChiCTR2000030481	75	Randomized (static)	Not available	Interventional
2020-001827-15	72	Randomized	Double	Interventional
2020-001307-16	104	Randomized	Open label	Interventional
2020-001395-15	1000	Randomized	Double	Interventional
2020-001622-64	200	Randomized	Open label	Interventional
2020-001934-37	200	Randomized	Open label	Interventional
2020-001413-20	100	Randomized	Open label	Interventional
2020-001445-39	84	Randomized	Open label	Interventional

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