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Table 1 Bioactive phytochemicals in Hyptis suaveolens and their pharmacological effects

From: A review on the phytochemical and pharmacological properties of Hyptis suaveolens (L.) Poit

Phytochemical constituents Bioactive chemical compound Pharmacological effect References
Phenolics Rosamarinic acid and Methyl rosamarinate Antioxidative and anti-cancer property ( by acting as free radical scavenger, hydrogen donar, metal chelators), protects human body from free radicals and oxidative stress [18, 22,23,24,25,26,27, 48, 49]
Flavonoids Apigenin, Naringenin, Querecetin, Rutin Hepatoprotective activity [24, 35, 36]
Hesperidin, Apigenin, Aluteolin Anti-inflammatory and Anti-analgesic activity [38, 39]
Terpenoids Limonene, Diterpenoids Suaveolol, Suaveolic acid, 5 alpha-Androst-9(LL)-En-12 Antifungal activity, Antibacterial (Inhibits growth of Gram +ve and Gram -ve bacteria). [39, 50,51,52]
Diterpenoids 13alpha-epi-dioxiabiet-8(14)-en-ol Antiplasmodic activity [42, 53, 54]
Alpha-pinene, beta-pinene, terpinolene, sabinene, beta cryophillene Larvicidal activity against Aedes albopictus larvae. [55]
Urosolic acid Antiviral activity against AIDS virus and SARC-CoV2 Virus [5, 9, 44, 56,57,58,59]