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Table 2 Antipyretic activity of methanol leaves extract of A. auriculiformis (MEAA) and standard drug

From: Scrutinizing pharmacological efficiency for Acacia auriculiformis by experimental and computational approach

Dose Initial temp (°C) Temp of 18 h during pyrexia 1 h 2 h 3 h 4h
Control 37.24 ± 0.03 38.07 ± 0.27 38.15 ± 0.35 38.15 ± 0.23 38.09 ± 0.15 38.05 ± 0.25
Paracetamol 36.94 ± 0.28 a 38.55 ± 0.35 a 37.68 ± 0.17 b 36.85 ± 0.73 b 36.48 ± 0.33 c 36.41 ± 0.55 c
200mg/kg 37.09 ± 0.23 a 38.15 ± 0.35 a 38.07 ± 0.291 a (7.55%) 37.98 ± 0.27 a (16.04%) 37.63 ± 0.37 b (49.1%) 38.02 ± 0.2 a (12.3%)
400mg/kg 36.7 ± 0.37 a 38.61 ± 0.28 a 38.54 ± 0.267 a (3.66%) 38.35 ± 0.03 a (13.61%) 38.15 ± 0.08 a
(24.08%)
38.24 ± 0.03 a (19.37%)
  1. Values are expressed as mean ± SEM (n = 3); ap < 0.05, bp < 0.01, cp < 0.001 significantly different in comparison with control. The data were analysed by ANOVA followed by Dunnett’s test