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Future Journal of Pharmaceutical Sciences

Table 2 Lipinski rule of five

From: In vitro antibacterial and in silico docking studies of two Schiff bases on Staphylococcus aureus and its target proteins

Parameters

Schiff bases

Condition for drug-like property

DmChDp

DmChDa

Mass

322

290

< 500

Hydrogen bond donor

2

0

< 5

Hydrogen bond acceptor

4

2

< 10

log P

5.15

5.74

< 5

Molar Refractivity

98.03

94.7

40–130

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