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Table 4 Forced degradation studies

From: Stability indicating thin-layer chromatographic method for estimation of antidiabetic drug Remogliflozin etabonate

Type of degradation Stress condition Time Percentage amount of drug (%) Rf values of degradation product
Base degradation 0.1 N NaOH, 25 °C 30 min 0 0.46
Base degradation 0.1 N NaOH, 25 °C 5 min 75.45 0.46
Acid degradation 0.1 N HCl, 70 °C 30 min 64.84 0.39
Oxidative stress degradation 3% H2O2, 70 °C 30 min 81.08 0.43
Dry heat degradation 70 °C 2 h 98.62 -
Photolytic degradation UV light 24 h 99.03 -