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Table 3 Draize score evaluation criteria for skin irritation study

From: Design and optimization of nano invasomal gel of Glibenclamide and Atenolol combination: in vitro and in vivo evaluation

Value Erythema Value Edema formation
0 No erythema 0 No edema
1 Very slight erythema, 1 Very slight edema
2 Slight erythema 2 Slight edema
3 Moderate to severe erythema 3 Moderate edema (1 mm)
4 Severe erythema 4 Severe edema