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Table 3 Effect PNFC and PNFEA of fractions on total cholesterol, total proteins, LPO, CAT, and SOD in CCl4-induced rats

From: Hepatoprotective activity of Phyllanthus niruri Linn. endophytes

Groups

Dose (mg/kg)

Total cholesterol (mg/dl)

Total proteins (mg/dl)

LPO level (μmol/mg protein)

CAT level (μmol/mg protein)

SOD level (μmol/mg protein)

Control

2 ml/kg

69.83 ± 0.30

5.78 ± 0.04

0.09 ± 0.003

0.32 ± 0.008

0.48 ± 0.009

CCl4 treated

2 ml/kg

79.06 ± 0.82***

6.23 ± 0.07**

0.15 ± 0.005***

0.11 ± 0.006***

0.15 ± 0.02***

Silymarin

25 mg/kg

65.15 ± 0.98

5.46 ± 0.08

0.09 ± 0.0006**

0.18 ± 0.002*

0.28 ± 0.022***

PNFC

50 mg/kg

73.29 ± 0.82

5.36 ± 0.04**

0.11 ± 0.004*

0.15 ± 0.01**

0.26 ± 0.015**

PNFC

100 mg/kg

69.43 ± 0.70

5.30 ± 0.07**

0.10 ± 0.001***

0.21 ± 0.006**

0.30 ± 0.02***

PNFEA

50 mg/kg

73.49 ± 0.98

6.07 ± 0.05*

0.12 ± 0.001*

0.21 ± 0.07***

0.31 ± 0.014**

PNFEA

100 mg/kg

71.73 ± 0.40

5.31 ± 0.06**

0.10 ± 0.005*

0.25 ± 0.01*

0.32 ± 0.02**

  1. The data were expressed as mean ± S.E.M. for six rats in each group. Statistical comparison were performed by one-way ANOVA followed by Turkey’s post test
  2. *P < 0.05, **P < 0.01, and ***P < 0.001 compared to normal control-treated group