Table 7 Force degradation study results
Stress degradation type | Conditions | Xylometazoline HCl | Ipratropium bromide |
|---|---|---|---|
Acid degradation | 0.1N HCl | 4.0% | 13.80% |
Base degradation | 0.1N NaOH | No degradation | 18% |
Oxidative degradation | 30% H2O2 | 2.4% | 6.70% |
Thermal degradation | At 80 °C for 48 h | No degradation | 6.0% |