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Table 5 Results of intraday and inter-day precision of standard solution

From: Concurrent estimation of lamivudine, tenofovir disoproxil fumarate, and efavirenz in blended mixture and triple combination tablet formulation by a new stability indicating RP-HPLC method

Precision

S.NO

LAM

TDF

EVZ

tR

Peak area

tR

Peak area

tR

Peak area

Intraday

1

2.646

2,717,067

4.411

1,786,776

5.964

1,235,921

2

2.658

2,696,080

4.418

1,776,006

5.955

1,235,063

3

2.642

2,704,851

4.396

1,780,791

5.924

1,240,927

4

2.644

2,692,168

4.391

1,774,513

5.913

1,235,911

5

2.644

2,699,839

4.390

1,778,441

5.909

1,240,942

Mean

2.647

2,702,001

4.401

1,779,305

5.933

1,237,753

SD

0.01

9637.5

0.01

4811.9

0.03

2925.3

%RSD

0.24

0.36

0.29

0.27

0.42

0.24

Inter-day

 Day 1

1

2.646

2,717,067

4.411

1,786,776

5.964

1,235,921

2

2.65

2,632,428

4.388

1,799,791

5.899

1,202,415

 Day 2

1

2.648

2,637,342

4.391

1,805,023

5.907

1,203,026

2

2.652

2,647,962

4.398

1,812,939

5.917

1,209,358

 Day 3

1

2.65

2,641,549

4.398

1,806,413

5.914

1,205,118

2

2.65

2,644,845

4.393

1,810,105

5.903

1,207,765

 

Mean

2.649

2,653,532

4.397

1,803,508

5.917

1,210,601

SD

0.002

31,605

0.008

9349

0.024

12,690

%RSD

0.08

1.19

0.18

0.52

0.40

1.05

  1. SD standard deviation, %RSD relative standard deviation, tR retention time