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Future Journal of Pharmaceutical Sciences

Table 8 Results of % assay of the tablet dosage form

From: Concurrent estimation of lamivudine, tenofovir disoproxil fumarate, and efavirenz in blended mixture and triple combination tablet formulation by a new stability indicating RP-HPLC method

Drug

Peak name

Retention time

Peak area

USP tailing

USP plate count

%Assay

LAM

Standard

2.64

2,691,283

1.22

2902

99.2

Test

2.65

2,690,079

1.21

2993

TDF

Standard

4.41

1,832,027

1.04

9631

99.6

Test

4.40

1,831,359

1.04

9057

EVZ

Standard

5.964

1,217,278

0.94

11,737

99.2

Test

5.903

1,217,069

0.94

11,261

  1. Average weight of the tablet, 1520mg
  2. % Purity of LAMI standard (API), 99.4
  3. % Purity of TDF standard (API), 99.4
  4. % Purity of EFV standard (API), 99.3
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