Table 1 Studied parameters and their theoretical specification limits [28]
Incidence | Symbol | Parameter name | Symbol | Unit | LSL | USL |
|---|---|---|---|---|---|---|
Dimension | D | Bulk density | ρb | g/mL | 0 | 1 |
Tapped density | ρt | g/mL | 0 | 1 | ||
Compressibility | ѱc | Carr's index | Carr | % | 0 | 50 |
Interparticle porosity | Ie | - | 0 | 1.2 | ||
Cohesion index | Icd | N | 0 | 200 | ||
aFriability | Fr | % | 1 | 0 | ||
Flowability | ѱf | Hausner’s ratio | HR | - | 3 | 1 |
Powder flow | t" | Sec | 0 | 10 | ||
Angle of repose | ϴr | ° | 50 | 0 | ||
Lubricity/stability | Cs | Loss on drying | %H | % | 0 | 10 |
Hygroscopicity | %RH | % | 20 | 0 | ||
Lubricity/dosage | ϕp | Particle size <75μm | %Pf | % | 50 | 0 |
Homogeneity index | Iϴ | - | 0 | 0.02 |