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Table 2 Mean polygon radii values of the various studied parameters

From: Application of SeDeM Expert System in the development of novel directly compressible co-processed excipients via co-processing

Parameter

Symbol

Corn starch

Microcrystalline cellulose

Starch-MCC composites

StarLac®

MicroceLac®100

Bulk density

ρb

5.22

3.81

5.62

5.39

4.69

Tapped density

ρt

8.40

4.42

6.93

6.77

5.72

Carr's index

Carr

2.43

7.27

6.21

5.91

6.41

Interparticle porosity

Ie

1.65

0.43

0.88

0.92

0.70

aCohesion index

Icd

0.00

9.74

7.09

6.36

7.15

bFriability

Fr

0.00

9.69

6.44

6.73

8.60

Hausner's ratio

HR

6.95

9.21

8.82

8.71

8.90

Powder flow

t"

4.39

6.52

7.91

7.72

8.59

Angle of repose

ϴr

2.11

4.01

6.61

6.43

6.94

Loss on drying

%H

10.00

7.17

7.26

9.20

5.57

Hygroscopicity

%RH

5.35

5.59

6.06

7.36

8.88

Particle size <75μm

%Pf

0.01

0.00

7.47

7.85

8.54

Homogeneity index

5.87

5.57

10.00

7.73

8.30

  1. aCohesion index value was mean of six determinations. bFriability was determined once. For all other parameters, determinations were conducted in triplicate