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Table 3 Incidence values of the studied excipients

From: Application of SeDeM Expert System in the development of novel directly compressible co-processed excipients via co-processing

Incidence

Symbol

Corn starch

MCC

Starch-MCC composites

StarLac®

MicroceLac®100

Compressibility function

ѱc

1.02a ±0.01b

6.78 ±0.03

5.16 ±0.14

4.98±0.03

5.72±0.11

Flowability function

ѱf

4.48±0.06

6.58±0.34

7.78±0.17

7.62±0.29

8.14±0.09

Powder stability

Cs

7.68 ±1.25

6.38±0.22

6.66±0.85

8.28±1.30

7.23±2.34

Lubricity/dosage

Ï•p

2.94±0.33

2.78±0.22

8.74±0.17

7.79±0.02

8.42±0.86

Parameter profile

IP

0.46

0.62

0.92

0.92

0.85

Parametric profile index

IPP

4.03±0.23

5.65±0.08

6.72±0.27

6.70±0.15

6.85±0.03

Good compression index

IGC

3.87±0.23

5.43±0.08

6.46±0.26

6.44±0.14

6.58±0.03

  1. For all parameters a and b are mean and standard deviations of triplicate determinations, respectively