From: A rapid RP-HPLC method for the simultaneous estimation of Ivacaftor and Tezacaftor and in silico study of their metabolitic products
Name
miLogP
TPSA
Natoms
MW
Nrotb
Volume
Tezacaftor
2.8
111.49
36
510.51
10
435.38
Tezacaftor M1
3.97
102.19
37
518.49
4
424.95
Tezacaftor M2
3.39
130.25
38
534.49
8
436.98