Future Journal of Pharmaceutical Sciences

Table 21 Biological spectrum of Ivaacaftor, Tezacaftor, and its metabolites

From: A rapid RP-HPLC method for the simultaneous estimation of Ivacaftor and Tezacaftor and in silico study of their metabolitic products

Probability	Ivacaftor	Ivacaftor M1	Ivacaftor M6	Tezacaftor	Tezacaftor M1	Tezacaftor M2
Pa	0.609	0.534	0.589	0.265	0.463	0.600
Pi	0.003	0.003	0.003	0.075	0.005	0.002

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