Homology modelling and analysis of structure predictions of human tumour necrosis factor ligand superfamily member 8

Future Journal of Pharmaceutical Sciences

Table 1 Top 10 threading templates used by I-TASSER

Rank	PDB Hit	Iden1	Iden2	Cov	Norm. Z-score
1	4msvA	0.20	0.18	0.57	1.27
2	4msvA	0.19	0.18	0.56	1.91
3	4msvA	0.21	0.18	0.56	1.71
4	3it8	0.22	0.15	0.59	2.77
5	3it8	0.23	0.15	0.59	2.06
6	4msvA	0.19	0.18	0.56	1.76
7	2re9	0.21	0.17	0.57	3.00
8	2e7aA	0.23	0.14	0.58	1.83
9	6iy9A	0.20	0.25	0.89	0.87
10	2re9A	0.22	0.17	0.56	3.75

Ident1 percentage sequence identity of the templates in the threading aligned region with the query sequence, Ident2 percentage sequence identity of the whole template chains with query sequence, Cov the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein, Norm. Z-score normalized Z-score of the threading alignments. Alignment with a normalized Z-score > 1 mean a good alignment and vice versa