Fig. 7From: Design, synthesis and biological evaluation of substituted pyrazoles endowed with brominated 4-methyl 7-hydroxy coumarin as new scaffolds against Alzheimer’s diseaseElectrostatic interaction of donepezil in the active site of AchE [ The standard drug donepezil contributed all hydrogen bonding with Tyr(tyrosine) and Thr (threonine)]Back to article page