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Table 4 IC50 value for the inhibition of MAO-A and MAO-B by the compound D1 and reference inhibitor

From: Design, synthesis and biological evaluation of substituted pyrazoles endowed with brominated 4-methyl 7-hydroxy coumarin as new scaffolds against Alzheimer’s disease

Treatment

Maximum % inhibition

IC50

MAO-A

MAO-B

MAO-A

MAO-B

Compound D1

61%

65%

2.4

3.5

Reference inhibitor

60%

65%

3.9

4.4