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Table 1 Levels and the experimental condition for Box Behnken design

From: Design expert as a statistical tool for optimization of 5-ASA-loaded biopolymer-based nanoparticles using Box Behnken factorial design

Factor Designation Low level (−) Mid-level (0) High level (+)
A Concentration of drug (% w/v) 0.1 0.3 0.5
B Concentration of chitosan (% w/v) 0.1 0.15 0.2
C Concentration of carboxymethyl inulin (CMI) (% w/v) 0.06 0.08 0.1