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Table 1 Levels and the experimental condition for Box Behnken design

From: Design expert as a statistical tool for optimization of 5-ASA-loaded biopolymer-based nanoparticles using Box Behnken factorial design

Factor

Designation

Low level (−)

Mid-level (0)

High level (+)

A

Concentration of drug (% w/v)

0.1

0.3

0.5

B

Concentration of chitosan (% w/v)

0.1

0.15

0.2

C

Concentration of carboxymethyl inulin (CMI) (% w/v)

0.06

0.08

0.1