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Table 5 Statistical analysis result of entrapment efficiency

From: Design expert as a statistical tool for optimization of 5-ASA-loaded biopolymer-based nanoparticles using Box Behnken factorial design

Source Sum of squares df Mean square F-value p-value  
Model 1221.73 9 135.75 1018.11 < 0.0001 Significant
A-CH 882.00 1 882.00 6615.00 < 0.0001  
B-CMI 200.00 1 200.00 1500.00 < 0.0001  
C-5-ASA 128.00 1 128.00 960.00 < 0.0001  
AB 1.0000 1 1.0000 7.50 0.0409  
AC 1.0000 1 1.0000 7.50 0.0409  
BC 1.0000 1 1.0000 7.50 0.0409  
A2 0.6410 1 0.6410 4.81 0.0798  
B2 3.10 1 3.10 23.27 0.0048  
C2 4.33 1 4.33 32.50 0.0023  
Residual 0.6667 5 0.1333    
Lack of fit 0.0000 3 0.0000 0.0000 1.0000 Not significant
Pure error 0.6667 2 0.3333    
Cor Total 1222.40 14