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Table 5 Statistical analysis result of entrapment efficiency

From: Design expert as a statistical tool for optimization of 5-ASA-loaded biopolymer-based nanoparticles using Box Behnken factorial design

Source

Sum of squares

df

Mean square

F-value

p-value

 

Model

1221.73

9

135.75

1018.11

< 0.0001

Significant

A-CH

882.00

1

882.00

6615.00

< 0.0001

 

B-CMI

200.00

1

200.00

1500.00

< 0.0001

 

C-5-ASA

128.00

1

128.00

960.00

< 0.0001

 

AB

1.0000

1

1.0000

7.50

0.0409

 

AC

1.0000

1

1.0000

7.50

0.0409

 

BC

1.0000

1

1.0000

7.50

0.0409

 

A2

0.6410

1

0.6410

4.81

0.0798

 

B2

3.10

1

3.10

23.27

0.0048

 

C2

4.33

1

4.33

32.50

0.0023

 

Residual

0.6667

5

0.1333

   

Lack of fit

0.0000

3

0.0000

0.0000

1.0000

Not significant

Pure error

0.6667

2

0.3333

   

Cor Total

1222.40

14

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