Table 3 Proton NMR assignments of pipemidic acid and its metal complexes
From: Synthesis, characterization, and antibacterial studies of pipemidic acid metal complexes
Drug complexed with | Ethyl group | Piperazinyl group | Ring proton of position 2 | Ring proton of position 5 | Carboxylic | ||
|---|---|---|---|---|---|---|---|
CH2 | CH3 | CH2 | CH2 | ||||
Reference drug | 2.47 | 1.34 | 2.77 | 3.33 | 8.94 | 3.81 | 9.17 |
Magnesium | 2.54 | 1.27 | 2.79 | 3.30 | 8.87 | 3.88 | 9.51 |
Calcium | 2.47 | 1.34 | 2.84 | 3.32 | 8.84 | 3.93 | 9.45 |
Chromium | 2.58 | 1.29 | 2.87 | 3.27 | 8.82 | 3.90 | 9.48 |
Manganese | 2.56 | 1.31 | 2.81 | 3.28 | 8.91 | 3.84 | 9.50 |
Iron | 2.53 | 1.28 | 2.84 | 3.27 | 8.87 | 3.87 | 9.52 |
Cobalt | 2.48 | 1.33 | 2.82 | 3.31 | 8.94 | 3.88 | 9.46 |
Nickel | 2.53 | 1.29 | 2.87 | 3.32 | 8.90 | 3.89 | 9.49 |
Copper | 2.49 | 1.34 | 2.87 | 3.30 | 8.96 | 4.00 | 9.56 |
Zinc | 2.57 | 1.36 | 2.85 | 3.26 | 8.85 | 3.82 | 9.53 |
Cadmium | 2.55 | 1.31 | 2.80 | 3.29 | 8.89 | 3.92 | 9.59 |