Antidiabetic effect of aqueous stem bark extract of Parinari macrophylla in alloxan-induced diabetic Wistar rats

Future Journal of Pharmaceutical Sciences

Table 3 Effect of aqueous stem bark extract of P. macrophylla on blood glucose levels in alloxan-induced diabetic Wistar rats

Group (n = 5)	Treatment given	Dose	Blood glucose levels (mg/dl)
Group (n = 5)	Treatment given	Dose	Week 0	Week 1	Week 2
1	Normal control (distilled water)	10 ml/kg	85.40 ± 0.60^a	88.20 ± 1.98^a	88.00 ± 8.00^a
2	Diabetic control (glibenclamide)	10 mg/kg	277.25 ± 60.82^b	179.00 ± 20.61^ab	188.25 ± 40.68^a
3	PMAE	1000 mg/kg	281.25 ± 23.17^b	152.25 ± 6.31^ac	149.75 ± 6.93^a
4	PMAE	2000 mg/kg	250.50 ± 29.83^b	171.50 ± 24.36^b	102.25 ± 6.96^a

Values are presented in mean ± SEM; PMAE, Parinari macrophylla aqueous stem bark extract; values in the same column having different letters of alphabets are statistically significant (p < 0.05)