Table 4 Pharmacological properties of isolated compounds from C. ambrosioides L

(−)-(2S,4S)-p-Mentha-2,8-dien-1-hydroperoxide

Trypanocidal

Toxicity against epimastigotes of Trypanosoma cruzi

[182]

(−)-(1S,4S)-p-Mentha-2,8-dien-1-hydroperoxide

Trypanocidal

Toxicity against epimastigotes of Trypanosoma cruzi

[182]

4-Hydroxy-4(α or β)-isopropyl-2-methyl-2-cyclohexen-1-one

Anti-inflammatory

Inhibition of NO production of LPS-stimulated Raw macrophages

[183]

α-Terpinene

Antimicrobial

Reduction of efflux pump in Staphylococcus aureus

[244, 245]

Myorelaxant

Inhibition of contraction induced by potassium, acetylcholine, or serotonin in rats.

[197]

Ascaridole

Antimalarial

Inhibition of the growth and development of Plasmodium falciparum

[246]

Analgesic

Prolongation of anesthesia effect and protection against writhings induced by using acetic acid in mice

[187]

Sedative

Reduction of locomotor activity in mice

[187]

Antifungal

Inhibition of the growth of Sclerotium rolf

[186]

Cytotoxic

Inhibition of human lymphoblastic leukemia T, promyelocytic leukemia, and breast cancer cells.

[247]

Trypanocidal

Toxicity against epimastigotes of Trypanosoma cruzi

[182]

Cytotoxicity

Redox-active iron in mammalian cells and mitochondria

[248]

Insecticidal

Contact toxicity and fumigation against Sitophilus zeamais adults

[188]

Insecticidal

Toxicity to male Blattella germanica

[217]

Caryophyllene oxide

Cytotoxicity

Inhibition of the respiratory chain in mammalian cells and mitochondria

[248]

Chenopodiumamine A and C

Anti-inflammatory

Significant inhibition against LPS induced TNF-α or IL-6 gene expressions

[190]

Chenopodiumamine A and C

Antioxidant

Inhibition against malondialdehyde

[190]

Isoascaridole

Insecticidal

Toxicity to male Blattella germanica

[217]

Cis-p-Menthadiene-l(7),8ol-2

Antifungal

Inhibition the growth of Sclerotium rolf

[186]

Kaempferol-3,7-dirhamnoside

Antihypertensive

Induction of hypotension in genetically prone hypertensive rats

[243]

Kaempferol 3-O-α-l-¹C₄-rhamnosyl-(1‴→2″)-β-d-⁴C₁-xylopyranoside

Antioxidant

Radical scavenging activity SC₅₀

[175]

Neral

Anticancer

Cytotoxicity on HaCaT cell line

[222]

p-Cymene

Insecticidal

Toxicity to male Blattella germanica

[217]

Scutellarein-7-O-α-rhamnopyranosyl-(1→2)-α-rhamnopyranosyl-(1→2)-α-rhamnopyranoside

Antioxidant

Radical scavenging activity

[180]

Scutella-rein-7-O-α-rhamnopyranosyl-(1→2)-α-rhamnopyranoside

Antioxidant

Radical scavenging activity

[180]