Batches | Factor A | Factor B | Factor C | Factor D | Response | |||
---|---|---|---|---|---|---|---|---|
Polyethylene oxide | Cellulose Acetate | Polyethylene glycol 6000 | Orifice diameter | % drug release at 2 h (Acid stage) | % drug release at 5 h (Buffer stage) | % drug release at 11 h (Buffer stage) | % drug release at 20 h (Buffer stage) | |
mg | % ratio | % ratio | mm | % | % | % | % | |
TSP1 | 250 | 94 | 6 | 0.6 | 20 | 42 | 66 | 97 |
TSP2 | 250 | 94 | 6 | 0.6 | 18 | 43 | 65 | 96 |
TSP3 | 300 | 97 | 3 | 0.5 | 4 | 19 | 46 | 96 |
TSP4 | 200 | 91 | 3 | 0.5 | 10 | 25 | 65 | 100 |
TSP5 | 200 | 97 | 9 | 0.5 | 14 | 32 | 76 | 98 |
TSP6 | 200 | 91 | 9 | 0.7 | 42 | 65 | 82 | 100 |
TSP7 | 300 | 91 | 3 | 0.5 | 12 | 22 | 50 | 95 |
TSP8 | 300 | 91 | 9 | 0.5 | 14 | 52 | 70 | 94 |
TSP9 | 200 | 91 | 3 | 0.7 | 14 | 28 | 68 | 99 |
TSP10 | 300 | 97 | 9 | 0.5 | 12 | 32 | 58 | 95 |
TSP11 | 200 | 97 | 3 | 0.5 | 7 | 23 | 58 | 99 |
TSP12 | 300 | 97 | 3 | 0.7 | 5 | 17 | 43 | 92 |
TSP13 | 250 | 94 | 6 | 0.6 | 22 | 39 | 67 | 97 |
TSP14 | 300 | 97 | 9 | 0.7 | 15 | 36 | 61 | 93 |
TSP15 | 250 | 94 | 6 | 0.6 | 25 | 45 | 71 | 98 |
TSP16 | 300 | 91 | 3 | 0.7 | 10 | 27 | 50 | 92 |
TSP17 | 200 | 91 | 9 | 0.5 | 45 | 71 | 85 | 99 |
TSP18 | 300 | 91 | 9 | 0.7 | 19 | 43 | 65 | 96 |
TSP19 | 200 | 97 | 9 | 0.7 | 12 | 28 | 72 | 100 |
TSP20 | 200 | 97 | 3 | 0.7 | 8 | 21 | 60 | 100 |